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In 2019, Crizanlizumab, a P-selectin inhibitor, was approved by the FDA for the prevention of vaso-occlusive crises in patients with sickle cell disease (Figure 1)
Dermatologists recommend taking the drips under medical supervision only, avoiding over-the-counter or unauthorized providers
Always apply broad-spectrum SPF30+ sunscreen during the day when using this cream to protect brightening results and prevent new discoloration
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